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Comprehensive analysis of the mitral valve

Mitral Valve

Highlights

  • Reliable anatomic measurements of the annulus [1] Read more 

  • ​Excellent agreement across conditions including MAC and existing AV devices [2][3] Read more

  • ​​Advanced mitral leaflet analysis

  • Various left chamber dimensions, functional and volumetric measurements

Latest News

30th October, 2024

MUNICH, GERMANY, October 30, 2024 / LARALAB GmbH, a pioneer in AI-driven medical imaging for cardiology and heart surgery, announces the launch of its new Mitral Valve Module. This addition to LARALAB’s suite is CE marked and marks a significant advancement in screening and decision-making for transcatheter mitral valve repair and replacement (TMVR). | Read press release| Read the press release

10th October, 2024

TCTMD highlights: "AI-Based CT Can Accurately Screen Patients for TMVR", presented by Dr. Martin Beyer (UKE Hamburg)| Read the article by TCTMD

AI and Measurement Performance

Study: A fully automated AI-based Software for Structural Mitral Valve CT-Analysis [1]
60 patient dataset from UKE Hamburg, thereof 25 with moderate to severe MAC and 24 with prior SAVR or TAVR.

Measurement
LARALAB (Mean±SD)
Expert (Mean±SD)
ICC
Mitral Annular Perimeter (mm)
125.2±14.0
124.6±14.0
0.92 (0.87-0.95)
Mitral Annular Area (mm^2)
1108±259.4
1108.8±263.8
0.94 (0.90-0.96)
Intercommisural Distance (mm)
41.8±4.8
41.1±5.1
0.92 (0.85-0.95)
Septolateral Diameter (mm)
32.8±4.8
31.8±4.7
0.91 (0.85-0.95)

[1] Beyer, Martin et al. "A Fully Automated AI-Based Software for Structural Mitral Valve CT-Analysis". EACTS Lison (2024). Access here.

Study: Streamlining Transcatheter Mitral Valve Replacement Screening [2][3]
181 patient dataset from 4 hospitals, all with severe MR.

Measurement
LARALAB (Mean±SD)
Expert (Mean±SD)
ICC
Mitral annular perimeter (mm)
116.8±17.4
114.2±18.3
0.94 (0.91-0.96)
Intercommisural distance (mm)
39.0±6.2
38.9±6.4
0.87 (0.84-0.89)
Septolateral diameter (mm)
29.7±5.7
29.1±5.4
0.89 (0.86 - 0.91)
Minimal enddystolic LVOT-area (mm^2)
341.6±163.1
326.0±171.8
0.80 (0.73 - 0.86)

[3] Matti Adam, et al. Streamlining Transcatheter Mitral Valve Replacement Screening: A Comparative Analysis of Fully Automatic AI-Based CT Analysis Versus Manual Core-Lab Approach. New York Valves (2024). Access here. 

Publications

10th October 2024

[1] Beyer, Martin et al. "A Fully Automated AI-Based Software for Structural Mitral Valve CT-Analysis". EACTS Lisbon (2024) |Read it here

10th October 2024

[2] Beyer, Martin et al. "Streamlining Transcatheter Mitral Valve Replacement Screening: A Comparative Analysis of Fully Automated AI - Based CT Analysis versus Manual Core - Lab Approach". EACTS (2024) | Read it here

4th June 2024

[3] Adam, Matti et al. "Streamlining Transcatheter Mitral Valve Replacement Screening: A Comparative Analysis of Fully Automated AI - Based CT Analysis versus Manual Core - Lab Approach". New York Valves (2024) |Read it here

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