Fully automated Neo-LVOT analysis for TMVR
TMVR Screening
Highlights
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Automated NeoLVOT with high level of agreement [1]
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Full-phase analysis and 3-dimensional NeoLVOT
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Precise measurements for MAC Cases [1]
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Leaflet and papillary muscle analysis
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Rapid pre-screening with REC | Read more about REC
Latest News
7th November, 2024
Abbott meets LARALAB: Rapid AI-based TMVR screening of the Tendyne ™ Valve is demonstrated live in collaboration with Abbott at DGK Kardiale Bildgebung in Cologne.
30th October, 2024
MUNICH, GERMANY, October 30, 2024 / LARALAB GmbH, a pioneer in AI-driven medical imaging for cardiology and heart surgery, announces the launch of its new Mitral Valve Module. This addition to LARALAB’s suite is CE marked and marks a significant advancement in screening and decision-making for transcatheter mitral valve repair and replacement (TMVR). | Read press release| Read the press release
10th October, 2024
Dr. Martin Beyer (UKE Hamburg) presents "excellent agreement" for AI-based analysis and "high accuracy" for TMVR pre-screening for TMVR | Read it here
10th October, 2024
TCTMD highlights: "AI-Based CT Can Accurately Screen Patients for TMVR", presented by Dr. Martin Beyer (UKE Hamburg)| Read the article by TCTMD
4th June, 2024
NY Valves Conference - REC Pre-Screening resulted in "reliable anatomical measurements" and "good accuracy compared to Abbott core lab decision making" for Tendyne, presented by Dr. Jonathan Curio (University Hospital Cologne) and validated with the University Hospitals of Cologne, Hamburg and Frankfurt| Read more
AI and Measurement Performance
Study: A fully automated AI-based Software for Structural Mitral Valve CT-Analysis [1]
60 patient dataset from UKE Hamburg, thereof 25 with moderate to severe MAC and 24 with prior SAVR or TAVR.
Measurement | LARALAB (Mean±SD) | Expert (Mean±SD) | ICC |
|---|---|---|---|
Mitral Annular Perimeter (mm) | 125.2±14.0 | 124.6±14.0 | 0.92 (0.87-0.95) |
Mitral Annular Area (mm^2) | 1108±259.4 | 1108.8±263.8 | 0.94 (0.90-0.96) |
Intercommisural Distance (mm) | 41.8±4.8 | 41.1±5.1 | 0.92 (0.85-0.95) |
Septolateral Diameter (mm) | 32.8±4.8 | 31.8±4.7 | 0.91 (0.85-0.95) |
Study: Streamlining Transcatheter Mitral Valve Replacement Screening [2][3]
181 patient dataset from 4 hospitals, all with severe MR.
Measurement | LARALAB (Mean±SD) | Expert (Mean±SD) | ICC |
|---|---|---|---|
Mitral annular perimeter (mm) | 116.8±17.4 | 114.2±18.3 | 0.94 (0.91-0.96) |
Intercommisural distance (mm) | 39.0±6.2 | 38.9±6.4 | 0.87 (0.84-0.89) |
Septolateral diameter (mm) | 29.7±5.7 | 29.1±5.4 | 0.89 (0.86 - 0.91) |
Minimal enddystolic LVOT-area (mm^2) | 341.6±163.1 | 326.0±171.8 | 0.80 (0.73 - 0.86) |
[2] Beyer, Martin et al. "Streamlining Transcatheter Mitral Valve Replacement Screening: A Comparative Analysis of Fully Automated AI - Based CT Analysis versus Manual Core - Lab Approach". EACTS (2024) | Access here.
[3] Matti Adam, et al. Streamlining Transcatheter Mitral Valve Replacement Screening: A Comparative Analysis of Fully Automatic AI-Based CT Analysis Versus Manual Core-Lab Approach. New York Valves (2024). Access here.
Publications
10th October 2024
[1] Beyer, Martin et al. "A Fully Automated AI-Based Software for Structural Mitral Valve CT-Analysis". EACTS Lisbon (2024) |Read it here
10th October 2024
[2] Beyer, Martin et al. "Streamlining Transcatheter Mitral Valve Replacement Screening: A Comparative Analysis of Fully Automated AI - Based CT Analysis versus Manual Core - Lab Approach". EACTS (2024) |Read it here
4th June 2024
[3] Adam, Matti et al. "Streamlining Transcatheter Mitral Valve Replacement Screening: A Comparative Analysis of Fully Automated AI - Based CT Analysis versus Manual Core - Lab Approach". New York Valves (2024) |Read it here